Levetiracetam-induced interstitial lung disease in a patient with advanced lung cancer

被引：2

作者：

Sato, Shintaro ^{[1
]}

Oba, Tomohiro ^{[1
]}

Ohta, Hiroki ^{[1
]}

Tsukahara, Yuta ^{[1
]}

Kida, Gen ^{[1
]}

Tsumiyama, Emiri ^{[1
]}

Kusano, Kenji ^{[1
]}

Nishizawa, Tomotaka ^{[1
]}

Kawabe, Rie ^{[1
]}

Yamakawa, Hideaki ^{[1
]}

Akasaka, Keiichi ^{[1
]}

Amano, Masako ^{[1
]}

Matsushima, Hidekazu ^{[1
]}

机构：

[1] Saitama Red Cross Hosp, Dept Resp Med, Saitama, Japan

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2020年 / 31卷

关键词：

Drug-induced interstitial lung disease; Levetiracetam; Lung cancer; ORGANIZING PNEUMONIA; BRONCHIOLITIS OBLITERANS; EOSINOPHILIC PNEUMONIA; BRAIN METASTASES; TUMORS; HYPERSENSITIVITY; ANTICONVULSANTS; PROPHYLAXIS; SEIZURES;

D O I：

10.1016/j.rmcr.2020.101241

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

An 85-year-old woman with antibiotics-resistant pneumonia after surgery for metastatic brain tumor from lung cancer was consulted to our department. Chest CT showed diffuse GGO bilaterally. BALF showed elevated ratios of lymphocytes and CD4/CD8. Tests for bacteria, mycobacteria, and fungi were negative. She improved following levetiracetam discontinuance and systemic corticosteroid administration, and we diagnosed levetiracetam-induced lung injury. Although levetiracetam is widely used, few reports of levetiracetam-induced pneumonia exist. Changes in chest images may occur after levetiracetam administration if patients have multiple risk factors for development of drug-induced interstitial lung disease. Bronchoscopy is useful for differential diagnosis if new lung lesions appear after starting levetiracetam.

引用

页数：5

共 50 条

[21] Prediction of postoperative exacerbation of interstitial pneumonia in patients with lung cancer and interstitial lung disease
Iyoda, Akira
Jiang, Shi-Xu
Amano, Hideki
Ogawa, Fumihiro
Matui, Yoshio
Kurouzu, Naomi
Hara, Hidenori
Nezu, Kenji
Mikami, Tetsuo
Saegusa, Makoto
Satoh, Yukitoshi
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2011, 2 (06) : 1073 - 1076
[22] Association between glucose intolerance and chemotherapy-induced lung injury in patients with lung cancer and interstitial lung disease
Otani, Toshihito
Yamaguchi, Kakuhiro
Nakao, Satoshi
Sakamoto, Shinjiro
Horimasu, Yasushi
Masuda, Takeshi
Miyamoto, Shintaro
Nakashima, Taku
Iwamoto, Hiroshi
Fujitaka, Kazunori
Hamada, Hironobu
Hattori, Noboru
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2021, 88 (05) : 857 - 865
[23] Chronic obstructive pulmonary disease and interstitial lung disease in patients with lung cancer
Mizuno, Satoko
Takiguchi, Yuichi
Fujikawa, Ayako
Motoori, Ken
Tada, Yuji
Kurosu, Katsushi
Sekine, Yasuo
Yanagawa, Noriyuki
Hiroshima, Kenzo
Muraoka, Katsumi
Mitsushima, Toru
Niki, Noboru
Tanabe, Nobuhiro
Tatsumi, Koichiro
Kuriyama, Takayuki
RESPIROLOGY, 2009, 14 (03) : 377 - 383
[24] Interstitial Lung Disease in HIV
Doffman, Sarah R.
Miller, Robert F.
CLINICS IN CHEST MEDICINE, 2013, 34 (02) : 293 - +
[25] Successful Drug Rechallenge Following Severe Acute Alectinib-induced Interstitial Lung Disease in a Patient With Advanced ALK-rearranged Lung Adenocarcinoma
Gadotti, Luiza Lara
Nogueira Amorim Canedo, Felipe Sales
Silva Almeida Ribeiro, Mauricio Fernando
Sacardo, Karina Perez
Saddi, Rodrigo
Machado Alessi, Joao Victor
Testagrossa, Leonardo de Abreu
Katz, Artur
CLINICAL LUNG CANCER, 2021, 22 (03) : E481 - E486
[26] Pivotal role of the HMGB1/sRAGE axis in drug-induced lung injury in advanced lung cancer with pre-existing interstitial lung disease
Nakao, Satoshi
Kakuhiro, Yamaguchi
Sakamoto, Shinjiro
Horimasu, Yasushi
Masuda, Takeshi
Miyamoto, Shintaro
Nakashima, Taku
Iwamoto, Hiroshi
Ohshimo, Shinichiro
Fujitaka, Kazunori
Hamada, Hironobu
Hattori, Noboru
EUROPEAN RESPIRATORY JOURNAL, 2020, 56
[27] Interstitial Lung Disease Induced by Pazopanib Treatment
Ide, Shotaro
Sakamoto, Noriho
Hara, Shintaro
Hara, Atsuko
Kakugawa, Tomoyuki
Nakamura, Yoichi
Futsuki, Yoji
Izumikawa, Koichi
Ishimatsu, Yuji
Yanagihara, Katsunori
Mukae, Hiroshi
INTERNAL MEDICINE, 2017, 56 (01) : 79 - 83
[28] Drug-induced interstitial lung disease
Spagnolo, Paolo
Bonniaud, Philippe
Rossi, Giulio
Sverzellati, Nicola
Cottin, Vincent
EUROPEAN RESPIRATORY JOURNAL, 2022, 60 (04)
[29] Association between glucose intolerance and chemotherapy-induced lung injury in patients with lung cancer and interstitial lung disease
Toshihito Otani
Kakuhiro Yamaguchi
Satoshi Nakao
Shinjiro Sakamoto
Yasushi Horimasu
Takeshi Masuda
Shintaro Miyamoto
Taku Nakashima
Hiroshi Iwamoto
Kazunori Fujitaka
Hironobu Hamada
Noboru Hattori
Cancer Chemotherapy and Pharmacology, 2021, 88 : 857 - 865
[30] Fatal Asymmetric Interstitial Lung Disease after Erlotinib for Lung Cancer
Ren, Shaohua
Li, Yuan
Li, Weiwen
Zhao, Zhongwei
Jin, Chunxian
Zhang, Dengke
RESPIRATION, 2012, 84 (05) : 431 - 435

← 1 2 3 4 5 →