FEASIBILITY OF USING ELASTOGRAPHY ULTRASOUND IN PEDIATRIC LOCALIZED SCLERODERMA (MORPHEA)

被引：9

作者：

Perez, Manuela ^{[1
,2
]}

Zuccaro, Jennifer ^{[3
,4
]}

Mohanta, Arun ^{[1
]}

Tijerin, Marta ^{[5
]}

Laxer, Ronald ^{[6
,7
,8
]}

Pope, Elena ^{[7
,8
,9
]}

Doria, Andrea S. ^{[1
,2
,8
]}

机构：

[1] Hosp Sick Children, Dept Diagnost Imaging, Toronto, ON, Canada

[2] Univ Toronto, Dept Med Imaging, 66 Bay St S,Apt 615, Toronto, ON, Canada

[3] Hosp Sick Children, Div Plast & Reconstruct Surg, Toronto, ON, Canada

[4] Univ Toronto, Fac Med, Inst Med Sci, Toronto, ON, Canada

[5] Hosp Univ Cent Asturias, Radiol Dept, Oviedo, Spain

[6] Hosp Sick Children, Div Rheumatol, Toronto, ON, Canada

[7] Hosp Sick Children, Div Pediat Med, Sect Dermatol, Toronto, ON, Canada

[8] Hosp Sick Children, Res Inst, Toronto, ON, Canada

[9] Univ Toronto, Dept Pediat, Toronto, ON, Canada

来源：

ULTRASOUND IN MEDICINE AND BIOLOGY | 2020年 / 46卷 / 12期

关键词：

Acoustic radiation force imaging; Elastography; Ultrasound; Localized scleroderma; Morphea; Pediatric; CLINICAL-APPLICATIONS; OUTCOME MEASURE; SKIN STIFFNESS; CHILDREN; ULTRASONOGRAPHY; QUANTIFICATION; ADULTS; INDEX; DEEP; TOOL;

D O I：

10.1016/j.ultrasmedbio.2020.08.007

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Assessment and monitoring of inflammation and tissue damage is crucial in localized scleroderma (LS), but validated diagnostic tools are lacking. We aimed to determine the feasibility of using acoustic radiation force imaging ultrasound elastography in the assessment of pediatric-onset LS lesions. Conventional ultrasound and shear-wave elastography (SWE) imaging were used to characterize changes in pre-assigned LS lesions in 13 prospectively recruited participants. Contralateral sites were used as controls. Mean SWE values were compared. LS lesions were significantly stiffer than control sites in the dermis and the hypodermis using both parametric and non-parametric tests, before and after skin-thickness normalization. We show that SWE imaging is a feasible way to discriminate between normal skin and LS lesions in the pediatric population. (E-mail: manuela.perezmatta@mail.utoronto.ca) (C) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

引用

页码：3218 / 3227

页数：10

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