Comparison of dopamine and noradrenaline release in mouse prefrontal cortex, striatum and hippocampus using microdialysis

被引:116
作者
Ihalainen, JA
Riekkinen, P
Feenstra, MGP
机构
[1] Netherlands Inst Brain Res, NL-1105 AZ Amsterdam ZO, Netherlands
[2] Univ Kuopio, Dept Neurol & Neurosci, FIN-70211 Kuopio, Finland
[3] Kuopio Univ Hosp, FIN-70211 Kuopio, Finland
基金
芬兰科学院;
关键词
stress; novelty; handling; calcium-sensitivity;
D O I
10.1016/S0304-3940(99)00840-X
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In vivo release of dopamine (DA) and noradrenaline (NA) in mouse medial prefrontal cortex, medial striatum and hippocampus was characterized using in vivo microdialysis. Basal release of NA was similar in these areas, but DA in striatum was 13-30 times higher than in other areas. Unconditioned stimuli (handling, novelty) induced strong increases, except for striatal DA. Striatal NA was more sensitive to handling than NA in other areas. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:71 / 74
页数:4
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