Reversible addition-fragmentation chain transfer synthesis and micellar characteristics of biocompatible amphiphilic poly(vinyl acetate)-graft-poly(N-vinyl-2-pyrrolidone) copolymers

被引：23

作者：

Atanase, Leonard Ionut ^{[1
]}

Winninger, Jeremy ^{[1
]}

Delaite, Christelle ^{[1
]}

Riess, Gerard ^{[1
]}

机构：

[1] Univ Haute Alsace, Ecole Natl Super Chim Mulhouse, Lab Photochim & Ingn Macromol, F-68093 Mulhouse, France

来源：

EUROPEAN POLYMER JOURNAL | 2014年 / 53卷

关键词：

Poly(vinyl acetate); Poly(N-vinyl-2-pyrrolidone); Graft copolymers; Reversible addition-fragmentation chain transfer (RAFT); Micellization; VINYL-ACETATE; RADICAL POLYMERIZATION; BLOCK-COPOLYMERS; N-VINYLPYRROLIDONE; GRAFT-COPOLYMERS; PYRROLIDONE; ARCHITECTURES; CHEMISTRY; XANTHATES; POLYMERS;

D O I：

10.1016/j.eurpolymj.2014.01.029

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly(vinyl acetate)-graft-poly(N-vinyl-2-pyrrolidone) (PVAc-graft-PNVP) copolymers of low grafting density and with a constant PVAc backbone of DPn = 72, were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization. A poly(vinyl acetate-co-vinyl chloroacetate) P(VAc-co-VClAc) gradient copolymer, also prepared by RAFT, was used as a macromolecular chain transfer agent. For this purpose it was functionalized by substitution of chlorine groups by xanthate moieties. In the NVP "grafting-from" polymerization step, PVAc-graft-PNVP copolymers were obtained, with PNVP contents from 85 to 95 mol% and with, on the average, 2-3 grafts per backbone with DPn ranging from 196 to 530. Their self-aggregation in aqueous medium revealed the formation of star-like micelles, with, at 25 degrees C, a partially "frozen-in" PVAc core and a PNVP corona. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：109 / 117

页数：9

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