Synthesis and Antibacterial Activity of Copper(I) Complexes with Bisbenzoylthiourea

被引:2
|
作者
Zhao, Meng-Meng [1 ]
Dong, Xiu-Yan [1 ]
Li, Gang [1 ]
Yang, Xiao-Qin [1 ]
机构
[1] Lanzhou Jiaotong Univ, Sch Chem & Biol Engn, Lanzhou 730070, Peoples R China
关键词
Bisbenzoylthiourea; Complex; Synthesis; Antibacterial activity; CRYSTAL-STRUCTURE; PALLADIUM(II) COMPLEXES; NICKEL(II) COMPLEXES; ANTIFUNGAL ACTIVITY; THIOSEMICARBAZONES; COORDINATION; LIGANDS;
D O I
10.14233/ajchem.2014.15897
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Two copper(I) complexes, [Cu(L)] ClO4 (1) and [Cu(L) Cl]center dot C2H5OH (2), have been synthesized by the reaction of copper(II) perchlorate hexahydrate and copper(II) chloride dihydrate with N, N'-(1,2-dimethylene) bisbenzoylthiourea (L), respectively and characterized by elemental analyses as well as IR spectra and TG-DTA analyses. Antibacterial activity assays exhibit MIC50 values of the two copper(I) complexes comparable to standard drugs for both Gram-positive and Gram-negative bacteria, both of them show stronger antibacterial activity.
引用
收藏
页码:277 / 279
页数:3
相关论文
共 50 条
  • [1] Antibacterial Studies of Copper(I) Complexes with Benzoylthiourea Derivatives
    Zhao, Meng-Meng
    Dong, Xiu-Yan
    Yang, Yu-Hua
    Li, Gang
    Zhang, Yu-Jie
    Yang, Xiao-Qin
    ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (14) : 8102 - 8104
  • [2] Synthesis, Crystal Structures, and Antibacterial Activity of Cobalt and Copper Complexes With Tridentate Schiff Bases
    Du, Juan
    SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2012, 42 (10) : 1410 - 1414
  • [3] Synthesis of novel metal complexes with isonicotinoyl hydrazide and their antibacterial activity
    El-Tabl, Abdou S.
    El-Bahnasawy, Ramadan M.
    Shakdofa, M. M. E.
    Hamdy, Alaa El-Deen Abdalah Ibrahim
    JOURNAL OF CHEMICAL RESEARCH, 2010, (02) : 88 - 91
  • [4] Synthesis, Structures, and Antibacterial Activities of Cobalt(III) and Copper(II) Complexes with Schiff Bases
    Ren, Chong-Gui
    Zhou, Li
    SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2015, 45 (05) : 714 - 718
  • [5] Copper(II) and zinc(II) complexes with Hydrazone: Synthesis, crystal structure, Hirshfeld surface and antibacterial activity
    Santiago, Pedro H. O.
    Santiago, Mariana B.
    Martins, Carlos H. G.
    Gatto, Claudia C.
    INORGANICA CHIMICA ACTA, 2020, 508
  • [6] Synthesis, Antibacterial and Antileishmanial Activity, Cytotoxicity, and Molecular Docking of New Heteroleptic Copper(I) Complexes with Thiourea Ligands and Triphenylphosphine
    Saeed, A.
    Larik, F. A.
    Jabeen, F.
    Mehfooz, H.
    Ghumro, S. A.
    El-Seedi, H. R.
    Ali, M.
    Channar, P. A.
    Ashraf, H.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2018, 88 (03) : 541 - 550
  • [7] Synthesis, spectroscopic characterisation, thermal analysis, DNA interaction and antibacterial activity of copper(I) complexes with N, N'- disubstituted thiourea
    Chetana, P. R.
    Srinatha, B. S.
    Somashekar, M. N.
    Policegoudra, R. S.
    JOURNAL OF MOLECULAR STRUCTURE, 2016, 1106 : 352 - 365
  • [8] Synthesis, crystal structure and in vitro antibacterial activity of two novel silver(I) complexes
    Ruan, Banfeng
    Tian, Yupeng
    Zhou, Hongping
    Wu, Jieying
    Liu, Zhaodi
    Zhu, Chenhao
    Yang, Jiaxiang
    Zhu, Hailiang
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2009, 694 (18) : 2883 - 2887
  • [9] Silver(I) complexes with halo-substituted cyanoanilines: synthesis, characterization and antibacterial activity
    Qian, Wei
    Yuan, Hao-Kun
    Zhang, Ran
    Fang, Rui-Qin
    JOURNAL OF COORDINATION CHEMISTRY, 2016, 69 (23) : 3593 - 3602
  • [10] Synthesis, characterization, and antibacterial activity of vanadium(IV) complexes of hydroxamic acids
    Sharma, Neeraj
    Kumari, Meena
    Kumar, Vijay
    Chaudhry, S. C.
    Kanwar, S. S.
    JOURNAL OF COORDINATION CHEMISTRY, 2010, 63 (01) : 176 - 184