Nano-BBr3.SiO2: a novel highly efficient heterogeneous catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives

This article describes a simple protocol for the efficient synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives using aromatic aldehydes, ethyl acetoacetate and urea in the presence of nano-BBr3.SiO2 as a catalyst. The structural features of the synthesized compounds were characterized by m.p., IR, MS, H-1 NMR, C-13 NMR, and CHN elemental analysis. We synthesized nano-BBr3.SiO2 for the first time as a nanocatalyst and characterized it by XRD, SEM and TEM techniques. High yields, mild conditions, easy availability, reusability, and green chemistry were some advantages of using this catalyst.