Imaging cerebral blood flow through the intact rat skull with temporal laser speckle imaging

被引：199

作者：

Li, PC ^{[1
]}

Ni, SL ^{[1
]}

Zhang, L ^{[1
]}

Zeng, SQ ^{[1
]}

Luo, QM ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Wuhan Natl Lab Optoelect, Key Lab Biomed Photon, Minist Educ, Wuhan 430074, Peoples R China

来源：

OPTICS LETTERS | 2006年 / 31卷 / 12期

关键词：

D O I：

10.1364/OL.31.001824

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We discovered that laser speckle temporal contrast analysis (LSTCA) is able to access the two-dimensional (2D) cerebral blood flow velocity and vessel structure through the intact rat skull. It is demonstrated that LSTCA can significantly suppress the influence of the laser speckle from the stationary structure, such as the skull, and thus reveal the blood flow and morphology of blood vessels through the laser speckle images recorded from the intact rat skull. (c) 2006 Optical Society of America.

引用

页码：1824 / 1826

页数：3

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