Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness

被引：4

作者：

Delaney, Shannon L. ^{[1
,2
]}

Murray, Lilly A. ^{[1
,2
]}

Aasen, Claire E. ^{[1
]}

Bennett, Clair E. ^{[1
,2
]}

Brown, Ellen ^{[1
,2
]}

Fallon, Brian A. ^{[1
,2
]}

机构：

[1] Columbia Univ, Lyme & Tick Borne Dis Res Ctr, Irving Med Ctr, New York, NY 10032 USA

[2] Columbia Univ, Irving Med Ctr, New York State Psychiat Inst, New York, NY 10032 USA

来源：

FRONTIERS IN MEDICINE | 2020年 / 7卷

关键词：

Borrelia miyamotoi disease; relapsing fever borrelia; Lyme disease; serodiagnosis; post-treatment Lyme disease syndrome; borreliosis; RELAPSING FEVER; LYME-DISEASE; UNITED-STATES; TRANSMISSION; ATTACHMENT; DURATION; VECTOR;

D O I：

10.3389/fmed.2020.567350

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on the GlpQ IgG ELISA. Nearly all of the patients (98%) had no prior B. miyamotoi testing, indicating that clinicians rarely test for this emerging tick-borne pathogen. Compared to patients who solely tested positive for Lyme disease antibodies, patients with B. miyamotoi antibodies presented with significantly more sleepiness and pain. A prospective study is needed to ascertain the relationship between the presence of B. miyamotoi antibodies and persistent symptoms.

引用

页数：5

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