Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness

被引：4
作者：
Delaney, Shannon L. [1 ,2 ]
Murray, Lilly A. [1 ,2 ]
Aasen, Claire E. [1 ]
Bennett, Clair E. [1 ,2 ]
Brown, Ellen [1 ,2 ]
Fallon, Brian A. [1 ,2 ]
机构：
[1] Columbia Univ, Lyme & Tick Borne Dis Res Ctr, Irving Med Ctr, New York, NY 10032 USA
[2] Columbia Univ, Irving Med Ctr, New York State Psychiat Inst, New York, NY 10032 USA
来源：
FRONTIERS IN MEDICINE | 2020年 / 7卷
关键词：
Borrelia miyamotoi disease; relapsing fever borrelia; Lyme disease; serodiagnosis; post-treatment Lyme disease syndrome; borreliosis; RELAPSING FEVER; LYME-DISEASE; UNITED-STATES; TRANSMISSION; ATTACHMENT; DURATION; VECTOR;
D O I：
10.3389/fmed.2020.567350
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on the GlpQ IgG ELISA. Nearly all of the patients (98%) had no prior B. miyamotoi testing, indicating that clinicians rarely test for this emerging tick-borne pathogen. Compared to patients who solely tested positive for Lyme disease antibodies, patients with B. miyamotoi antibodies presented with significantly more sleepiness and pain. A prospective study is needed to ascertain the relationship between the presence of B. miyamotoi antibodies and persistent symptoms.
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页数：5
相关论文
共 27 条
  • [1] Posttreatment Lyme Disease Syndrome
    Aucott, John N.
    [J]. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2015, 29 (02) : 309 - +
  • [2] Post-treatment Lyme disease syndrome symptomatology and the impact on life functioning: is there something here?
    Aucott, John N.
    Rebman, Alison W.
    Crowder, Lauren A.
    Kortte, Kathleen B.
    [J]. QUALITY OF LIFE RESEARCH, 2013, 22 (01) : 75 - 84
  • [3] Niche Partitioning of Borrelia burgdorferi and Borrelia miyamotoi in the Same Tick Vector and Mammalian Reservoir Species
    Barbour, Alan G.
    Bunikis, Jonas
    Travinsky, Bridgit
    Hoen, Anne Gatewood
    Diuk-Wasser, Maria A.
    Fish, Durland
    Tsao, Jean I.
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2009, 81 (06) : 1120 - 1131
  • [4] Transmission of Borrelia miyamotoi sensu lato relapsing fever group spirochetes in relation to duration of attachment by Ixodes scapularis nymphs
    Brenner, Nicole E.
    Dolan, Marc C.
    Replogle, Adam J.
    Sexton, Christopher
    Hojgaard, Andrias
    Boegler, Karen A.
    Clark, Rebecca J.
    Eisen, Lars
    [J]. TICKS AND TICK-BORNE DISEASES, 2017, 8 (05) : 677 - 681
  • [5] Transmission of the relapsing fever spirochete, Borrelia miyamotoi, by single transovarially-infected larval Ixodes scapularis ticks
    Breuner, Nicole E.
    Hojgaard, Andrias
    Replogle, Adam J.
    Boegler, Karen A.
    Eisen, Lars
    [J]. TICKS AND TICK-BORNE DISEASES, 2018, 9 (06) : 1464 - 1467
  • [6] Centers for Disease Control and Prevention, 2019, DAT SURV
  • [7] Tick-borne relapsing fever in North America
    Dworkin, MS
    Schwan, TG
    Anderson, DE
    [J]. MEDICAL CLINICS OF NORTH AMERICA, 2002, 86 (02) : 417 - +
  • [8] Pathogen transmission in relation to duration of attachment by Ixodes scapularis ticks
    Eisen, Lars
    [J]. TICKS AND TICK-BORNE DISEASES, 2018, 9 (03) : 535 - 542
  • [9] The General Symptom Questionnaire-30 (GSQ-30): A Brief Measure of Multi-System Symptom Burden in Lyme Disease
    Fallon, Brian A.
    Zubcevik, Nevena
    Bennett, Clair
    Doshi, Shreya
    Rebman, Alison W.
    Kishon, Ronit
    Moeller, James R.
    Octavien, Nadlyne R.
    Aucott, John N.
    [J]. FRONTIERS IN MEDICINE, 2019, 6
  • [10] Fiorito TM, 2017, INFECT DIS CLIN PRAC, V25, P250, DOI 10.1097/IPC.0000000000000509
123