Phosphorylation of L-type Ca2+ channel β2a subunit induces cardiomyocyte hypertrophy

被引：0
|
作者：
Hayamizu, Nao [1 ]
Kumagai, Shohei [1 ]
Matsunami, Sachi [1 ]
Nakayama, Hiroyuki [1 ]
Fujio, Yasushi [1 ]
机构：
[1] Osaka Univ, Lab Clin Sci & Biomed, Sch Pharmaceut, Suita, Osaka, Japan
来源：
JOURNAL OF PHARMACOLOGICAL SCIENCES | 2014年 / 124卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：134P / 134P
页数：1
相关论文
共 50 条
  • [1] Increases in Ca2+ influx through the L-type Ca2+ channel induces pathological cardiomyocyte hypertrophy
    Chen, Xiongwen
    Nakayama, Hiroyuki
    Zhang, Hongyu
    Zhang, Xiaoying
    Harris, David M.
    Berretta, Remus M.
    Wilson, Rachel M.
    MacDonnell, Scott
    Kubo, Hajime
    Weisser-Thomas, Jutta
    Eckhart, Andrea D.
    Koch, Walter J.
    Molkentin, Jeffery D.
    Houser, Steven R.
    CIRCULATION, 2007, 116 (16) : 17 - 18
  • [2] Overexpression of the β2a subunit of the L-type Ca2+ channel in cultured adult ventricular myocytes increases the Ca2+ current and induces cell death
    Chen, XW
    Vanderpool, K
    Potts, ST
    Harris, DM
    Mills, GD
    Marsh, JD
    Houser, SR
    BIOPHYSICAL JOURNAL, 2004, 86 (01) : 110A - 111A
  • [3] Caveolae-Specific Phosphorylation of L-type Calcium Channel β2a Subunit Exacerbates Cardiac Hypertrophy
    Kumagai, Shohei
    Hayamizu, Nao
    Matsunami, Sachi
    Otsuka, Wataru
    Sakata, Yasushi
    Fujio, Yasushi
    Nakayama, Hiroyuki
    CIRCULATION, 2014, 130
  • [4] Pathological implication of phosphorylation of β2a, a subunit of L-type calcium channel in heart
    Otsuka, Wataru
    Kumagai, Shohei
    Tonegawa, Kota
    Obana, Masanori
    Nakayama, Hiroyuki
    Fujio, Yasushi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2016, 130 (03) : S113 - S113
  • [5] Ca2+ sensors of L-type Ca2+ channel
    Romanin, C
    Gamsjaeger, R
    Kahr, H
    Schaufler, D
    Carlson, O
    Abernethy, DR
    Soldatov, NM
    FEBS LETTERS, 2000, 487 (02) : 301 - 306
  • [6] Constitutive β2a phosphorylation modifies the basal properties of the L-type Ca2+ channel in HEK 293 cells
    Ganesan, AN
    O'Rourke, B
    BIOPHYSICAL JOURNAL, 2005, 88 (01) : 449A - 449A
  • [7] Decreased cardiac L-type Ca2+ channel activity induces hypertrophy and heart failure in mice
    Goonasekera, Sanjeewa A.
    Hammer, Karin
    Auger-Messier, Mannix
    Bodi, Ilona
    Chen, Xiongwen
    Zhang, Hongyu
    Reiken, Steven
    Elrod, John W.
    Correll, Robert N.
    York, Allen J.
    Sargent, Michelle A.
    Hofmann, Franz
    Moosmang, Sven
    Marks, Andrew R.
    Houser, Steven R.
    Bers, Donald M.
    Molkentin, Jeffery D.
    JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (01): : 280 - 290
  • [8] Ca2+ signaling in cardiac myocytes overexpressing the α1 subunit of L-type Ca2+ channel
    Song, LS
    Guia, A
    Muth, JN
    Rubio, M
    Wang, SQ
    Xiao, RP
    Josephson, IR
    Lakatta, EG
    Schwartz, A
    Cheng, HP
    CIRCULATION RESEARCH, 2002, 90 (02) : 174 - 181
  • [9] Palmitoylation of the cardiac L-type Ca2+ channel beta subunit and channel function
    Cuadra, AE
    Ma, H
    Ten Eick, RE
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2002, 34 (07) : A17 - A17
  • [10] The auxiliary subunit γ1 of the skeletal muscle L-type Ca2+ channel is an endogenous Ca2+ antagonist
    Andronache, Zoita
    Ursu, Daniel
    Lehnert, Simone
    Freichel, Marc
    Flockerzi, Veit
    Melzer, Werner
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (45) : 17885 - 17890
12345