Meningococcal C conjugate vaccine: The experience in England and Wales

被引:129
作者
Campbell, Helen [1 ]
Borrow, Ray [2 ]
Salisbury, David [3 ]
Miller, Elizabeth [1 ]
机构
[1] Hlth Protect Agcy Ctr Infect, Immunisat Hepatitis & Blood Safety Dept, London NW9 5EQ, England
[2] Manchester Royal Infirm, Hlth Protect Agcy NW, Meningococcal Reference Unit, Manchester M13 9WL, Lancs, England
[3] Dept Hlth, London SE1 6TE, England
关键词
Meningococcal serogroup C disease; Meningococcal C conjugate vaccine; Surveillance; INFLUENZAE TYPE-B; IMMUNOLOGICAL MEMORY; NEISSERIA-MENINGITIDIS; UNITED-KINGDOM; CHANGING EPIDEMIOLOGY; IMMUNIZATION CAMPAIGN; MASS IMMUNIZATION; VIRULENT CLONE; NO EVIDENCE; UK INFANTS;
D O I
10.1016/j.vaccine.2009.04.067
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Meningococcal C conjugate vaccine was introduced in the UK in November 1999 together with a comprehensive meningococcal surveillance strategy to support and inform the vaccine programme. These surveillance data have provided important information on the long-term effectiveness of the programme, through direct and indirect protection, and on the prevalent serotypes and serosubtypes causing invasive meningococcal infection subsequent to vaccine introduction. The MCC immunization programme has been extremely successful in controlling serogroup C disease and continues to be evaluated. The aim of this paper is to review the experiences in England and Wales over the past 9 years. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:B20 / B29
页数:10
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