Intraventricular cytarabine in a case of idiopathic hypertrophic pachymeningitis

被引:17
作者
Kleiter, I
Hans, VH
Schuierer, G
Marienhagen, J
Hau, P
Schütz, H
Bogdahn, U
Steinbrecher, A
机构
[1] Univ Regensburg, Dept Neurol, D-93042 Regensburg, Germany
[2] Univ Regensburg, Inst Neuroradiol, D-93042 Regensburg, Germany
[3] Univ Regensburg, Dept Nucl Med, D-93042 Regensburg, Germany
[4] Univ Bonn, Inst Neuropathol, D-5300 Bonn, Germany
[5] Stadt Kliniken Frankfurt Main Hochst, Dept Neurol, Frankfurt, Germany
关键词
D O I
10.1136/jnnp.2003.024653
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Idiopathic hypertrophic chronic pachymeningitis (IHCP) is characterised by inflammatory fibrotic thickening of the dura mater. Long term management is controversial. A 28 year old man with craniospinal IHCP and prominent lymphocytic meningitis is reported. Cerebrospinal fluid and histological examination suggested a CD4+ T cell driven process and B cell stimulation. After surgical, tuberculostatic, and immunosuppressive treatment failed to control the progressive meningeal hypertrophy, causing severe headache and neurological disability, the disease process eventually abated with intraventricular cytarabine treatment.
引用
收藏
页码:1346 / 1348
页数:3
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