Treatment of Behcet's disease with granulocyte and monocyte adsorption apheresis

被引：24

作者：

Kanekura, T

Gushi, A

Iwata, M

Fukumaru, S

Sakamoto, R

Kawahara, K

Maruyama, I

Kanzaki, T

机构：

[1] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Dermatol, Kagoshima 8908520, Japan

[2] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Lab Med, Kagoshima 8908520, Japan

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2004年 / 51卷 / 02期

关键词：

D O I：

10.1016/j.jaad.2003.12.023

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The painful orogenital ulcerations of Behcet's disease are among the major symptoms of patients and are often intractable. We assessed the efficacy of granulocyte and monocyte adsorption apheresis therapy in two patients, a 21-year-old man with orogenital ulcerations and a 50-year-old woman with genital ulceration and abdominal pain. They underwent 5 and 8 granulocyte and monocyte adsorption apheresis treatments at 5-day intervals, respectively. The painful orogenital ulcerations of the man responded dramatically, and the genital ulcer of the woman decreased in size and her abdominal pain was improved. Our results demonstrate that granulocyte and monocyte adsorption apheresis may he useful for treating orogenital ulcerations of Behcet's disease.

引用

页码：S83 / S87

页数：5

共 14 条

[1] A SUBPOPULATION OF MAC-1 (CD11B/CD18) MOLECULES MEDIATES NEUTROPHIL ADHESION TO ICAM-1 AND FIBRINOGEN [J].