Expert Review of the Evidence Base for Prevention of Travelers' Diarrhea

被引:71
作者
DuPont, Herbert L. [1 ,2 ,3 ,4 ]
Ericsson, Charles D. [2 ]
Farthing, Michael J. G. [5 ,6 ]
Gorbach, Sherwood [7 ,8 ,9 ]
Pickering, Larry K. [10 ]
Rombo, Lars [11 ]
Steffen, Robert [12 ]
Weinke, Thomas [13 ]
机构
[1] Univ Texas Sch Publ Hlth Houston, Ctr Infect Dis, Houston, TX 77030 USA
[2] Univ Texas Sch Med Houston, Div Infect Dis, Dept Internal Med, Houston, TX USA
[3] St Lukes Episcopal Hosp, Internal Med Serv, Houston, TX 77030 USA
[4] Baylor Coll Med, Dept Med, Houston, TX 77030 USA
[5] Univ Brighton, Brighton, E Sussex, England
[6] Sussex Med Sch, Brighton, E Sussex, England
[7] Tufts Univ, Sch Med, Dept Publ Hlth, Boston, MA 02111 USA
[8] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA
[9] Tufts Univ, Sch Med, Dept Microbiol, Boston, MA 02111 USA
[10] Emory Univ, Sch Med, Dept Pediat, Atlanta, GA USA
[11] Karolinska Inst, Malaria Res Lab, Stockholm, Sweden
[12] Univ Zurich, Zurich, Switzerland
[13] Klinikum Ernst von Bergmann Clin, Med Clin, Potsdam, Germany
关键词
ENTEROTOXIGENIC ESCHERICHIA-COLI; HEAT-LABILE TOXIN; IRRITABLE-BOWEL-SYNDROME; STATES-MILITARY PERSONNEL; NORTH-AMERICAN TRAVELERS; PEACE-CORPS VOLUNTEERS; ORAL CHOLERA VACCINES; BLIND CLINICAL-TRIAL; BISMUTH SUBSALICYLATE; UNITED-STATES;
D O I
10.1111/j.1708-8305.2008.00299.x
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The most frequent illness among persons traveling from developed to developing countries is travelers' diarrhea. Travelers to high-risk regions traditionally have been educated to exercise care in food and beverage selection. Innovative research is needed to identify ways to motivate people to exercise this care and to determine its value. Chemoprophylaxis can be recommended for certain groups while monitoring for safety, drug resistance, and efficacy against all forms of bacterial diarrhea. Research to evaluate the value of immunoprophylaxis is recommended. In the following document, the authors used an evidence base when available to determine strength and quality of evidence and when data were lacking, the panel experts provided consensus opinion.
引用
收藏
页码:149 / 160
页数:12
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