SHORT & EXPEDIENT SYNTHESIS OF PYRIDINE CONTAINING DIHYDROCHALCONE 1-(2-HYDROXYPHENYL)-3-(PYRIDIN-4-YL)PROPAN-1-ONE: A NON-NUTRITIVE ARTIFICIAL SWEETENER

被引：0

作者：

Rafi, Sheik ^{[1
]}

Kandagatla, Bhaskar ^{[1
]}

Darapaneni, Balachennaiah ^{[1
]}

Oruganti, Srinivas ^{[1
]}

机构：

[1] Dr Reddys Inst Life Sci, Hyderabad 500046, Andhra Pradesh, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 24卷 / 04期

关键词：

FRIES REARRANGEMENT; SENSORY EVALUATION; DERIVATIVES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of the artificial sweetener 1-(2-hydroxyphenyl)-3-(pyridin-4-yl)propan-1-one employing Fries Rearrangement as a key step in the construction of pyridine containing dihydrochalcone is reported. A novel approach for the synthesis of heteroaryl containing dihydrochalcones via Fries Rearrangement method is reported, and can serve as a general method for the preparation of a wide range of heteroaryl containing dihydrochalcones.

引用

页码：459 / 464

页数：6

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