A one-pot synthesis of 3-methyl-5-aryl-4H-pyrrolo[2,3-d]-isoxazoles

被引：45

作者：

Rajanarendar, E. ^{[1
]}

Mohan, G. ^{[1
]}

Ramesh, P. ^{[1
]}

Karunakar, D. ^{[1
]}

机构：

[1] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 28期

关键词：

sharpless epoxidation; epoxide ring-opening; cyclization; dehydration; one-pot synthesis;

D O I：

10.1016/j.tetlet.2006.04.145

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sharpless epoxidation of 4-amino-3-methyl-5-styrylisoxazoles 1 resulted in the formation of 3-methyl-5-aryl-4H-pyrrolo[2,3-d]-isoxazoles 4 in a one-step reaction. The reaction initially involves epoxide formation, followed by ring-opening and cyclization. Finally dehydration leads to the title compounds. The pyrrolo[2,3-d]-isoxazoles 4 were also synthesized via an alternative procedure. (c) 2006 Published by Elsevier Ltd.

引用

页码：4957 / 4959

页数：3

共 9 条

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