Sulfated tungstate a heterogeneous acid catalyst for synthesis of 4-aryl-NH-1,2,3-triazoles by 1,3-dipolar cycloaddition of nitroolefins with NaN3

被引：12
作者：
Autade, Snehalata B. [1 ]
Akamanchi, Krishnacharya G. [1 ]
机构：
[1] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Nathalal Parekh Marg, Mumbai 400019, Maharashtra, India
来源：
SYNTHETIC COMMUNICATIONS | 2019年 / 49卷 / 15期
关键词：
1; 3-Dipolar cycloaddition; heterogeneous catalysis; nitrostyrenes; sulfated tungstate; 2; 3-triazoles; ONE-POT SYNTHESIS; AZIDE-ALKYNE CYCLOADDITION; METAL-FREE; 3-COMPONENT REACTION; CLICK CHEMISTRY; 4,5-DISUBSTITUTED 1,2,3-(NH)-TRIAZOLES; REGIOSELECTIVE SYNTHESIS; TERMINAL ACETYLENES; ANTICANCER ACTIVITY; TRIAZOLE FORMATION;
D O I：
10.1080/00397911.2019.1612919
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and new method for the synthesis of 4-aryl-NH-1,2,3-triazoles from nitroolefins and NaN3 by 1,3-dipolar cycloaddition reaction, employing a mild solid inorganic acid sulfated tungstate as a heterogeneous catalyst, has been developed. The protocol emphasizes broad substrate scope with many functionalities, less reaction time, stability to open air, easy work-up, and with good to excellent yields.
引用
收藏
页码：1947 / 1956
页数：10
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