Electrochemical Biosensors for the Determination of Cardiovascular Markers: a Review

被引:55
作者
Pedrero, Maria [1 ]
Campuzano, Susana [1 ]
Pingarron, Jose M. [1 ]
机构
[1] Univ Complutense Madrid, Fac CC Quim, Dept Quim Analit, E-28040 Madrid, Spain
关键词
Cardiovascular diseases; Biomarkers; Electrochemical; Biosensors; ACID-BINDING PROTEIN; CARDIAC TROPONIN-I; C-REACTIVE PROTEIN; LABEL-FREE DETECTION; MULTIWALLED CARBON NANOTUBES; NATRIURETIC PEPTIDE; AMPEROMETRIC MAGNETOIMMUNOSENSOR; DISPOSABLE IMMUNOSENSOR; MULTIPLEXED DETECTION; SENSITIVE DETECTION;
D O I
10.1002/elan.201300597
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Nowadays there is a growing interest in the development of devices for the fast and reliable detection and quantification of biomarkers associated with cardiovascular diseases (CVDs). The main objective is not only an early diagnosis of these diseases but also predicting the risk that an individual can suffer CVD. Electrochemical biosensors can play a key role in the development of low cost, portable and rapid sensing platforms for this purpose. This review discusses critically the state of the art in the development, applications and potential suitability of electrochemical biosensors for the determination of cardiovascular biomarkers as well as the required characteristics that these sensors should fulfill to be finally accepted in the clinical community.
引用
收藏
页码:1132 / 1153
页数:22
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