Blood pressure impact on left ventricular geometry in chronic haemodialysis patients

Aim: Left ventricular hypertrophy in chronic haemodialysis patients is multifactorial. Our aim was to evaluate retrospectively the relationship between 24-h blood pressure monitoring and geometry and function of left ventricle (LV). Patients a methods: We examined 50 patients (men/women 33/17) treated by chronic haemodialysis (>3 months) aged 57.5 years (53-63; median, interquartile range). We measured blood pressure during 24 hours in short interdialytic period using Spacelab monitor 90217. Echocardiography was provided in short interdialytic period. Results: Left ventricular mass index significantly correlated with SBP (tau-b=0.21; p=0.030; 95% CI 0.01-0.42), DBP (tau-b=0.23; p=0.018; 95% CI 0.04-0.42) and MAP (tau-b=0.26; p=0.009; 95% CI 0.06-0.45). SBP, DBP, MAP and PP did add a significant information to the prediction of relative wall thickness. We did not find any relationship between BP and left ventricular ejection fraction, left ventricular enddiastolic diameter and left atrial size. Conclusion: We found out an important 24-hour blood pressure impact on left ventricular relative wall thickness and left ventricular mass index. Left ventricular ejection fraction, left ventricular enddiastolic diameter and left atrial size were not related to 24-hour blood pressure. We did not find a relationship between blood pressure and left ventricular enddiastolic diameter. From all diastolic parameters the strongest association was found between systolic blood pressure in all three phases and ratio of peak early to late diastolic filling velocity (Tab. 5, Ref. 19). Full Text in PDF www.elis.sk.