Thinking beyond the tumor cell:: Nf1 haploinsufficiency in the tumor environment

被引：25

作者：

McLaughlin, ME

Jacks, T

机构：

[1] MIT, Howard Hughes Med Inst, Dept Biol, Cambridge, MA 02139 USA

[2] MIT, Ctr Canc Res, Cambridge, MA 02139 USA

[3] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA

来源：

CANCER CELL | 2002年 / 1卷 / 05期

关键词：

D O I：

10.1016/S1535-6108(02)00078-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Deletion of both copies of the Nf1 gene in Schwann cells combined with Nf1 heterozygosity in the tumor environment promotes neurofibroma formation in mice.

引用

页码：408 / 410

页数：3

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