A silver-lined anniversary of Fleet iminosugars: 1984-2009, from DIM to DRAM to LABNAc

被引：83

作者：

Davis, Benjamin G. ^{[1
]}

机构：

[1] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England

来源：

TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 6-8期

基金：

英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

NARINGINASE L-RHAMNOSIDASE; LOOKING-GLASS INHIBITORS; STANNANE-MEDIATED HYDROXYMETHYLATION; RAY CRYSTAL-STRUCTURE; ALPHA-L-RHAMNOSIDASE; D-GLUCOSE; GLYCOSIDASE INHIBITORS; D-GULONOLACTONE; ENANTIOSPECIFIC SYNTHESIS; EFFICIENT SYNTHESIS;

D O I：

10.1016/j.tetasy.2009.03.013

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of iminosugars, polyhydroxylated N-heterocylces, has profoundly influenced the understanding of carbohydrate-processing and other enzyme systems. This review examines the prescient work over 25 years of one of the leading protagonists in the synthesis of these powerful compounds, examining strategy, detail and outcome. (C) 2009 Published by Elsevier Ltd.

引用

页码：652 / 671

页数：20

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