Post-transcriptional regulation of auxin transport proteins: cellular trafficking, protein phosphorylation, protein maturation, ubiquitination, and membrane composition

被引:123
作者
Titapiwatanakun, Boosaree [1 ]
Murphy, Angus S. [1 ]
机构
[1] Purdue Univ, Dept Hort, W Lafayette, IN 47907 USA
关键词
AUX; LAX; cellular trafficking; membrane composition; P-glycoprotein; phosphorylation; pin-formed; protein maturation; ubiquitination; LATERAL ROOT; PLASMA-MEMBRANE; ARABIDOPSIS-THALIANA; ABC TRANSPORTER; P-GLYCOPROTEIN; DEPENDENT CELL; TWISTED DWARF1; PIN PROTEINS; LIPID RAFTS; EFFLUX;
D O I
10.1093/jxb/ern240
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Auxin concentration gradients, established by polar transport of auxin, are essential for the establishment and maintenance of polar growth and morphological patterning. Three families of cellular transport proteins, PIN-formed (PIN), P-glycoprotein (ABCB/PGP), and AUXIN RESISTANT 1/LIKE AUX1 (AUX1/LAX), can independently and co-ordinately transport auxin in plants. Regulation of these proteins involves intricate and co-ordinated cellular processes, including protein-protein interactions, vesicular trafficking, protein phosphorylation, ubiquitination, and stabilization of the transporter complexes on the plasma membrane.
引用
收藏
页码:1093 / 1107
页数:15
相关论文
共 119 条
[1]   Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism [J].
Abas, L ;
Benjamins, R ;
Malenica, N ;
Paciorek, T ;
Wirniewska, J ;
Moulinier-Anzola, JC ;
Sieberer, T ;
Friml, J ;
Luschnig, C .
NATURE CELL BIOLOGY, 2006, 8 (03) :249-256
[2]   The power of the pump: Mechanisms of action of P-glycoprotein (ABCB1) [J].
Ambudkar, SV ;
Kim, IW ;
Sauna, ZE .
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2006, 27 (05) :392-400
[3]   Biochemical, cellular, and pharmacological aspects of the multidrug transporter [J].
Ambudkar, SV ;
Dey, S ;
Hrycyna, CA ;
Ramachandra, M ;
Pastan, I ;
Gottesman, MM .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1999, 39 :361-398
[4]   Modulation of P-glycoproteins by auxin transport inhibitors is mediated by interaction with immunophilins [J].
Bailly, Aurelien ;
Sovero, Valpuri ;
Vincenzetti, Vincent ;
Santelia, Diana ;
Bartnik, Dirk ;
Koenig, Bernd W. ;
Mancuso, Stefano ;
Martinoia, Enrico ;
Geisler, Markus .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (31) :21817-21826
[5]   Auxin influx carriers stabilize phyllotactic patterning [J].
Bainbridge, Katherine ;
Guyomarc'h, Soazig ;
Bayer, Emmanuelle ;
Swarup, Ranjan ;
Bennett, Malcolm ;
Mandel, Therese ;
Kuhlemeier, Cris .
GENES & DEVELOPMENT, 2008, 22 (06) :810-823
[6]   Interactions of PIN and PGP auxin transport mechanisms [J].
Bandyopadhyay, A. ;
Blakeslee, J. J. ;
Lee, O. R. ;
Mravec, J. ;
Sauer, M. ;
Titapiwatanakun, B. ;
Makam, S. N. ;
Bouchard, R. ;
Geisler, M. ;
Martinoia, E. ;
Friml, J. ;
Peer, W. A. ;
Murphy, A. S. .
BIOCHEMICAL SOCIETY TRANSACTIONS, 2007, 35 :137-141
[7]   Local, efflux-dependent auxin gradients as a common module for plant organ formation [J].
Benková, E ;
Michniewicz, M ;
Sauer, M ;
Teichmann, T ;
Seifertová, D ;
Jürgens, G ;
Friml, J .
CELL, 2003, 115 (05) :591-602
[8]   Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism [J].
Bennett, MJ ;
Marchant, A ;
Green, HG ;
May, ST ;
Ward, SP ;
Millner, PA ;
Walker, AR ;
Schulz, B ;
Feldmann, KA .
SCIENCE, 1996, 273 (5277) :948-950
[9]   Shoot-derived auxin is essential for early lateral root emergence in Arabidopsis seedlings [J].
Bhalerao, RP ;
Eklöf, J ;
Ljung, K ;
Marchant, A ;
Bennett, M ;
Sandberg, G .
PLANT JOURNAL, 2002, 29 (03) :325-332
[10]  
Blakeslee J J., 2005, Plant Endocytosis, P159