Collagen from Marine Biological Sources and Medical Applications

被引:184
作者
Felician, Fatuma Felix [1 ]
Xia, Chunlei [1 ]
Qi, Weiyan [1 ,2 ]
Xu, Hanmei [1 ,2 ]
机构
[1] China Pharmaceut Univ, Engn Res Ctr Peptide Drug Discovery & Dev, Nanjing 211198, Jiangsu, Peoples R China
[2] China Pharmaceut Univ, Coll Life Sci & Technol, Dept Marine Pharm, Nanjing 211198, Jiangsu, Peoples R China
关键词
application; bioactivity; collagen; marine source; peptides; ENZYME INHIBITORY PEPTIDES; JELLYFISH RHOPILEMA-ESCULENTUM; CHONDROSIA-RENIFORMIS NARDO; IN-VITRO ANTIOXIDANT; SQUID SKIN COLLAGEN; PROTEIN HYDROLYSATE; FERMENTED MILK; ANTIBACTERIAL ACTIVITY; SPONGE COLLAGEN; II COLLAGEN;
D O I
10.1002/cbdv.201700557
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Collagen is the most studied protein with a wide range of applications including pharmaceutical, biomedical, cosmetics, leather, and film industries due to its special characteristics that are high biocompatibility, good bioactivity, and weak antigenicity. Although collagen sources are abundant, the outbreak of varied diseases among land animals posed threat to its utilization in our daily life. Thus, a probe for an alternative source began, which in turn revealed the immense untapped marine sources, such as fish, jellyfish, and some marine Mammals. The present article deals with a brief description of collagen, its characteristics, marine sources, extraction, collagen peptides and their biological activities, potential use and application in various field.
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页数:18
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