A Short Overview on the Biomedical Applications of Silica, Alumina and Calcium Phosphate-based Nanostructured Materials

被引:29
作者
Ellahioui, Younes [1 ,2 ]
Prashar, Sanjiv [1 ]
Gomez-Ruiz, Santiago [1 ]
机构
[1] Univ Rey Juan Carlos, Dept Biol & Geol Fis & Quim Inorgan, Calle Tulipan S-N, E-28933 Mostoles, Madrid, Spain
[2] Univ Abdelmalek Essaadi, Dept Chim, Fac Sci, Tetouan, Morocco
关键词
Nanoparticles; silica; alumina; calcium phosphate; drug-delivery; biomedical; DRUG-DELIVERY SYSTEM; MESOPOROUS SILICA; SURFACE FUNCTIONALIZATION; HYDROTHERMAL SYNTHESIS; ANTICANCER APPLICATIONS; CANCER-CELLS; NANOPARTICLES; PARTICLES; HYDROXYAPATITE; CYTOTOXICITY;
D O I
10.2174/0929867323666161024153459
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This article reviews the use of silica, alumina and calcium phosphate-based nanostructured materials with biomedical applications. A short introduction on the use of the materials in Science, Nanotechnology and Health is included followed by a revision of each of the selected materials. A description of the principal synthetic methods used in the preparation of the materials in nanostructured form is included. The most widely used applications in biomedicine are reviewed including, for example drug-delivery, bone regeneration, imaging, sensoring amongst others. Finally, a short description of the toxicity and cytotoxicity associated with each of the materials of this revision is presented. This short literature revision serves to demonstrate the very promising future ahead of nanosystems based on silica, alumina and calcium phosphate for biological and biomedical applications.
引用
收藏
页码:4450 / 4467
页数:18
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