Bortezomib for Refractory Immune-Mediated Thrombocytopenia Purpura

被引：24

作者：

Beckman, Joan D. ^{[1
]}

Rollins-Raval, Marian A. ^{[2
]}

Raval, Jay S. ^{[2
]}

Park, Yara A. ^{[2
]}

Mazepa, Marshall ^{[2
]}

Ma, Alice ^{[1
]}

机构：

[1] Univ N Carolina, Div Hematol Oncol, Dept Med, 170 Manning Dr,CB 7305, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Pathol & Lab Med, Chapel Hill, NC USA

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2018年 / 25卷 / 02期

基金：

美国国家卫生研究院;

关键词：

immune-mediated thrombocytopenia purpura; bortezomib;

D O I：

10.1097/MJT.0000000000000517

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The treatment of refractory immune-mediated thrombocytopenia purpura (ITP) can be challenging. This case report describes treatment of refractory ITP with bortezomib, a proteasome inhibitor. This strategy has been successful in relapsing thrombotic thrombocytopenic purpura but is a novel therapeutic approach for ITP. Further research use of proteasome inhibition in refractory ITP may be warranted.

引用

页码：E270 / E272

页数：3

共 5 条

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