On the origin and frequency of Y chromosome deletions responsible for severe male infertility

被引：55

作者：

Edwards, RG ^{[1
]}

Bishop, CE ^{[1
]}

机构：

[1] BAYLOR COLL MED,DEPT MOL & HUMAN GENET,HOUSTON,TX 77030

来源：

MOLECULAR HUMAN REPRODUCTION | 1997年 / 3卷 / 07期

关键词：

deletions; meiosis; mosaicism; oligozoospermia; post-fertilization deletions;

D O I：

10.1093/molehr/3.7.549

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The origin of deletions associated with non-obstructive severe oligozoospermia in men are discussed. Deletions could arise during various stages of meiosis, at later stages in spermatids, or post-fertilization. Certain embryonic stages may be highly sensitive. The possibilities of an inherited propensity to these and other deletions, and of mosaicism in embryos are assessed.

引用

页码：549 / 554

页数：6

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