Genetic and educational assortative mating among US adults

被引:125
作者
Domingue, Benjamin W. [1 ]
Fletcher, Jason [3 ,4 ,5 ]
Conley, Dalton [6 ]
Boardman, Jason D. [1 ,2 ]
机构
[1] Univ Colorado, Inst Behav Sci, Boulder, CO 80309 USA
[2] Univ Colorado, Dept Sociol, Boulder, CO 80309 USA
[3] Univ Wisconsin, La Follette Sch Publ Affairs, Madison, WI 53706 USA
[4] Univ Wisconsin, Ctr Demog & Ecol, Madison, WI 53706 USA
[5] Univ Wisconsin, Dept Sociol, Madison, WI 53706 USA
[6] NYU, Ctr Genom & Syst Biol, New York, NY 10003 USA
基金
美国国家卫生研究院;
关键词
homophily; random mating; genetic homogamy; HERITABILITY; SELECTION; MARRIAGE; TRENDS;
D O I
10.1073/pnas.1321426111
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Understanding the social and biological mechanisms that lead to homogamy (similar individuals marrying one another) has been a long-standing issue across many fields of scientific inquiry. Using a nationally representative sample of non-Hispanic white US adults from the Health and Retirement Study and information from 1.7 million single-nucleotide polymorphisms, we compare genetic similarity among married couples to noncoupled pairs in the population. We provide evidence for genetic assortative mating in this population but the strength of this association is substantially smaller than the strength of educational assortative mating in the same sample. Furthermore, genetic similarity explains at most 10% of the assortative mating by education levels. Results are replicated using comparable data from the Framingham Heart Study.
引用
收藏
页码:7996 / 8000
页数:5
相关论文
共 32 条
[11]  
Falconer D.S., 1996, Quantitative Genetics, V4th
[12]   SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap [J].
Johnson, Andrew D. ;
Handsaker, Robert E. ;
Pulit, Sara L. ;
Nizzari, Marcia M. ;
O'Donnell, Christopher J. ;
de Bakker, Paul I. W. .
BIOINFORMATICS, 2008, 24 (24) :2938-2939
[13]  
Lieberson Stanley., 1988, From Many Strands: Ethnic and Racial Groups in Contemporary America
[14]   Mate Selection in Cyberspace: The Intersection of Race, Gender, and Education [J].
Lin, Ken-Hou ;
Lundquist, Jennifer .
AMERICAN JOURNAL OF SOCIOLOGY, 2013, 119 (01) :183-215
[15]   Robust relationship inference in genome-wide association studies [J].
Manichaikul, Ani ;
Mychaleckyj, Josyf C. ;
Rich, Stephen S. ;
Daly, Kathy ;
Sale, Michele ;
Chen, Wei-Min .
BIOINFORMATICS, 2010, 26 (22) :2867-2873
[16]   5 DECADES OF EDUCATIONAL ASSORTATIVE MATING [J].
MARE, RD .
AMERICAN SOCIOLOGICAL REVIEW, 1991, 56 (01) :15-32
[17]   The major histocompatibility complex, sexual selection, and mate choice [J].
Milinski, Manfred .
ANNUAL REVIEW OF ECOLOGY EVOLUTION AND SYSTEMATICS, 2006, 37 :159-186
[18]  
National Center for Biotechnology Information dbGaP, 2007, FRAM SNP HLTH ASS RE
[19]  
National Center for Biotechnology Information dbGaP, 2012, HLTH RET STUD
[20]  
Neale M.C. C. L., 2013, METHODOLOGY GENETIC, V67