Microcapsule assembly of human serum albumin at the liquid/liquid interface by the pendent drop technique

被引:38
作者
Lu, G [1 ]
An, ZH [1 ]
Tao, C [1 ]
Li, JB [1 ]
机构
[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Int Joint Lab,Key Lab Colloid & Interface Sci, Beijing 100080, Peoples R China
关键词
D O I
10.1021/la049564x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The use of pendent drop technique with a tiny capillary to produce protein capsules of the size of a few micrometers was discussed. It was found that the assembled human serum albumin (HSA) microcapsules recorded with a fluorescence microscope are stable and can be considered to coat many species. The species responsible for molecular recognition such as proteins, DNA or antibodies can be bound to the protein film to create biological recognition devices. It was concluded that the species can also be used as synthetic microreaction vessels, as templates for the growth, crystallization and precipitation of organic dyes, magnetic particles or as carriers in drug delivery.
引用
收藏
页码:8401 / 8403
页数:3
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