Novel finding of high density of activated mast cells in endometrial polyps

被引：57

作者：

Al-Jefout, Moamar ^{[1
,2
,3
]}

Black, Kirsten ^{[1
,2
]}

Schulke, Lauren ^{[1
,2
]}

Berbic, Marina ^{[1
]}

Luscombe, Georgina ^{[1
]}

Tokushige, Natsuko ^{[1
]}

Manconi, Frank ^{[1
]}

Markham, Robert ^{[1
]}

Fraser, Ian S. ^{[1
,2
]}

机构：

[1] Univ Sydney, Queen Elizabeth II Res Inst Mothers & Infants, Dept Obstet & Gynaecol, Sydney, NSW 2006, Australia

[2] Royal Prince Alfred Hosp, Camperdown, NSW 2050, Australia

[3] Mutah Univ, Mutah Med Fac, Al Karak, Jordan

来源：

FERTILITY AND STERILITY | 2009年 / 92卷 / 03期

关键词：

MENSTRUAL-CYCLE; EXPRESSION;

D O I：

10.1016/j.fertnstert.2009.02.016

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues. (Fertil Steril (R) 2009; 92:1104-6. (C)2009 by American Society for Reproductive Medicine.)

引用

页码：1104 / 1106

页数：3

共 14 条

[1]

[Anonymous], J REPROD MED

[2]

Cairns JA, 1996, J IMMUNOL, V156, P275

[3] ESTRADIOL ENHANCES INVITRO THE HISTAMINE-RELEASE INDUCED BY EMBRYONIC HISTAMINE-RELEASING FACTOR (EHRF) FROM UTERINE MAST-CELLS [J].