Two new hirsutane-type sesquiterpenoids chondrosterins N and O from the marine fungus Chondrostereum sp.

被引：7

作者：

Huang, Lei ^{[1
]}

Lan, Wen-Jian ^{[2
,3
]}

Li, Hou-Jin ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem, Guangzhou, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou, Guangdong, Peoples R China

[3] Guangdong Technol Res Ctr Adv Chinese Med, Guangzhou, Guangdong, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2018年 / 32卷 / 13期

关键词：

Chondrostereum sp; chondrosterin; hirsutane; sesquiterpenoid; CHEMOENZYMATIC TOTAL-SYNTHESIS; NATURAL-PRODUCTS; TOLUENE;

D O I：

10.1080/14786419.2017.1389935

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The marine fungus Chondrostereum sp. was collected from a soft coral Sarcophyton tortuosum from the South China Sea. This fungus was cultured in glucose-peptone-yeast (GPY) medium and the culture broth was extracted with EtOAc. By the method of H-1 NMR pre-screening and tracing the diagnostic proton signals of the methyl groups, two new hirsutane-type sesquiterpenoids, chondrosterins N and O (1 and 2) were isolated from the metabolite extracts. Their structures were elucidated on the basis of MS, 1D and 2D NMR data. [GRAPHICS] .

引用

页码：1578 / 1582

页数：5

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