A Stimuli-Responsive Rotaxane-Gold Catalyst: Regulation of Activity and Diastereoselectivity

被引：118

作者：

Galli, Marzia ^{[1
]}

Lewis, James E. M. ^{[1
]}

Goldup, Stephen M. ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 46期

基金：

英国工程与自然科学研究理事会;

关键词：

catalysts; gold; molecular machines; rotaxanes; supramolecular chemistry; MOLECULAR MACHINES; SWITCHABLE ORGANOCATALYST; TERMINAL ALKYNES; LIGANDS; CYCLOPROPANATION; ACTIVATION; CATENANES; HYDROALKOXYLATION; PHOSPHINE; CHEMISTRY;

D O I：

10.1002/anie.201505464

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A rotaxane-based Au catalyst was developed and the effect of the mechanical bond on its behavior was studied. Unlike the non-interlocked thread, the rotaxane requires a catalytically innocent cofactor, the identity of which significantly influences both the yield and diastereoselectivity of the reaction. Under optimized conditions, Au-I (the catalyst), Ag-I (to abstract the Cl- ligand), and Cu-I (the cofactor) combine to produce a catalyst with excellent activity and selectivity.

引用

页码：13545 / 13549

页数：5

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