A facile preparation of (2,4,6-14C-cyanuric acid under solvent-free conditions

被引：4

作者：

Patil, SP ^{[1
]}

Padmanabhan, D ^{[1
]}

机构：

[1] BARC Vashi Complex, Board Radiat & Isotope Technol, LC ILCJP, Mumbai 400705, India

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2002年 / 45卷 / 07期

关键词：

C-14-urea; (2,4,6-C-14)-cyanuric acid; ammonium chloride fusion under vacuum;

D O I：

10.1002/jlcr.579

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

(2,4,6-C-14)-Cyanuric acid was prepared from C-14-urea by the heterocyclization of the latter in the presence of ammonium chloride. This procedure involves solvent-free fusing of the reactants in a vacuum sealed glass tube. The product was purified by ion-exchange column chromatography using Sephadex SE C-25. A radiochemical yield of 60.5% was obtained based on C-14-urea and the product had a specific activity of 19.06 mCi/mmol. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：539 / 542

页数：4