Efficacy of concomitant use of dexmedetomidine and propofol in tetanus

被引：12

作者：

Miya, Ken ^{[1
]}

Shimojo, Nobutake ^{[1
]}

Koyama, Yasuaki ^{[1
]}

Enomoto, Yuki ^{[1
]}

Hagiya, Keiichi ^{[1
]}

Yamasaki, Yuichiro ^{[1
]}

Nishino, Tomofumi ^{[1
]}

Kawano, Satoru ^{[1
]}

Mizutani, Taro ^{[1
]}

机构：

[1] Univ Tsukuba, Dept Emergency & Crit Care Med, Tsukuba, Ibaraki 3058575, Japan

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2015年 / 33卷 / 12期

关键词：

MANAGEMENT; PATIENT;

D O I：

10.1016/j.ajem.2015.04.069

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Tetanus is an infectious disease caused by Clostridium tetani, which manifests systemic convulsion and autonomic instability associated with high case fatality. Despite proper medical intervention, management of those symptoms is often difficult. We report a case of 67-year-old man with tetanus in which a concomitant use of dexmedetomidine, an adrenaline alpha-2 receptor agonist, and propofol, a GABA(A) receptor binding agent, was successful in the management of systemic convulsion and autonomic instability without necessitating conventional anticonvulsant, neuromuscular blocking agents, or tracheostomy.

引用

页码：1848.e3 / 1848.e4

页数：2

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