Asymmetric synthesis of 1-aminopentadecane-3,5,7,9,11,13,15-heptols and of 1,15-diaminopentadecane-3,5,7,9,11,13-hexols and derivatives

被引：0

作者：

Gerber-Lemaire, S ^{[1
]}

Popowycz, F ^{[1
]}

Glanzmann, C ^{[1
]}

Vogel, P ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Chim Mol & Biol, Lausanne, Switzerland

来源：

SYNTHESIS-STUTTGART | 2002年 / 14期

关键词：

aminopolyketide; asymmetric synthesis; diaminopolyketide; long-chain aminopolyols; 2,2 '-methylenedifuran;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from 2,2'-methylenedifuran, enantiomerically enriched (98%) (3R,5S,7R,9S,11R,13R)- and (3R,5S,7S,9R,11R,13R)-15-amino-5,7,9,11-tetrahydroxy-3,13-bis(4-methoxybenzoyloxy)pentadec-1-yl) pivalate were prepared as well as (3R,5R,7R,9R,11S,13S)-1,15-diamino-5,7,9,11-tetrahydroxypentadeca-3,13-diyl bis(4-methoxybenzoate) and (3R,5S,7S,9S,11R,13S)-1,15-diaminopentadecane-3,5,7,9,11,13-hexol.

引用

页码：1979 / 1986

页数：8