Stereoselective synthesis of (+)-isoindolo-β-carboline

被引：8

作者：

Wakchaure, Prasad B. ^{[1
]}

Puranik, Vedavati G. ^{[2
]}

Argade, Narshinha P. ^{[1
]}

机构：

[1] Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India

[2] Natl Chem Lab, Ctr Mat Characterizat, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 02期

关键词：

RING; OXIDATION; STRATEGY;

D O I：

10.1016/j.tetasy.2009.01.001

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Starting from homophthalic anhydride and (S)-tryptophan, the stereoselective synthesis of (+)-isoindolo-beta-carboline has been described via the corresponding homophthalimide, its chemoselective oxidative ring contraction, and the intramolecular dehydrative ring closure followed by a geometry-specific demethoxycarbonylation. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：220 / 224

页数：5

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