Chimpanzee homologous of human Y specific STRs -: A comparative study and a proposal for nomenclature

被引：45

作者：

Gusmao, L

González-Neira, A

Alves, C

Lareu, M

Costa, S

Amorim, A

Carracedo, A ^{[1
]}

机构：

[1] Univ Santiago de Compostela, Inst Legal Med, E-15705 Santiago De Compostela, Galicia, Spain

[2] IPATIMUP, P-4200 Oporto, Portugal

[3] Univ Porto, Fac Ciencias, P-4100 Oporto, Portugal

来源：

FORENSIC SCIENCE INTERNATIONAL | 2002年 / 126卷 / 02期

关键词：

Y-chromosome specific STRs; sequence data; nomenclature;

D O I：

10.1016/S0379-0738(02)00046-4

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Eleven Y specific microsatellites, previously studied in humans, were typed for fragment length and sequenced in chimpanzees (Pan troglodytes). The primers described by Ayub et al. (Nucleic Acids Res. 28, 2000, 2) for amplifying DYS434, DYS435, DYS436, DYS437, DYS438, DYS439 and those described by White et al. (Genomics, 57,1999,433) for GATA A10, A7.1, A7.2, C4, and H4, were used to amplify DNA samples from chimpanzees. Primers described for Y GATA A4 were found to amplify the same region as reported for DYS439. Moreover, the GATA A4 forward primer only matches the repeat flanking region in 14 of the 28 bp, being responsible for a very weak amplification. Therefore, this system was not included in this study. The analysis of the repeat and sequence structure observed in chimpanzee and human Y chromosomes allowed evolutionary comparisons as well as the basis for improving Y STR nomenclature and therefore, a unified nomenclature for these novel STRs is proposed to the scientific community following ISFG recommendations. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：129 / 136

页数：8

共 12 条

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[3]

GILL P, 2001, FORENSIC SCI INT, V114, P305

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