Adaptive Radiotherapy for Anatomical to Changes

被引：192
作者：
Sonke, Jan-Jakob [1 ]
Aznar, Marianne [2 ,3 ]
Rasch, Coen [4 ]
机构：
[1] Netherlands Canc Inst, Dept Radiat Oncol, Amsterdam, Netherlands
[2] Univ Manchester, Fac Biol Med & Hlth, Div Mol & Clin Canc Sci,Sch Med Sci, Manchester Canc Res Ctr,Manchester Acad Hlth Sci, Manchester, Lancs, England
[3] Manchester Acad Hlth Sci Ctr, Christie NHS Fdn Trust, Manchester, Lancs, England
[4] Univ Amsterdam, Acad Med Ctr, Dept Radiat Oncol, Amsterdam, Netherlands
来源：
SEMINARS IN RADIATION ONCOLOGY | 2019年 / 29卷 / 03期
关键词：
CONE-BEAM-CT; IMAGE-GUIDED RADIOTHERAPY; PLAN SELECTION STRATEGY; INTENSITY-MODULATED RADIOTHERAPY; RADIATION-THERAPY SMART; INVASIVE BLADDER-CANCER; CELL LUNG-CANCER; NECK-CANCER; COMPUTED-TOMOGRAPHY; QUALITY-ASSURANCE;
D O I：
10.1016/j.semradonc.2019.02.007
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The anatomy of cancer patients changes between radiation treatment planning and delivery as well as over the course of radiotherapy. Adaptive radiotherapy CARD aims to deliver radiation accurately and precisely in the presence of such changes. To that end, ART uses an imaging feedback loop to quantify these changes and modify the treatment plan accordingly. This paper provides an overview of anatomical changes occurring over the course of therapy and various adaptive strategies developed to account for those. Moreover, residual uncertainties present in adaptive radiotherapy are discussed as well as required tools, potential pitfalls and remaining challenges. (C) 2019 The Authors. Published by Elsevier Inc.
引用
收藏
页码：245 / 257
页数：13
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