Direct C-H functionalization of tetrahydro-γ-carbolines at the α-position

被引：1
作者：
Zhang, Yahui [1 ]
Chen, Yi [1 ]
Guo, Mei [1 ]
Sun, Ge [1 ]
Que, Rongbin [1 ]
Cui, Ranran [1 ]
Gao, Yu [1 ]
Chen, Haijun [1 ]
机构：
[1] FuZhou Univ, Key Lab Mol Synth & Funct Discovery, Coll Chem, Fujian Prov Univ, Fuzhou 350116, Fujian, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2022年 / 46卷 / 20期
关键词：
BETA-CARBOLINES; DERIVATIVES; AMINATION; BONDS; ACIDS;
D O I：
10.1039/d2nj00928e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The direct C-H functionalization of tetrahydro-gamma-carbolines (TH gamma Cs) at the alpha-position has been presented. This mild and simple strategy allows coupling of TH gamma Cs with various anilines and indoles with satisfactory to excellent yields. This two-step/one-pot method could be applied to synthesize complex compounds and is suitable for the C-H functionalization of similar biologically active structures.
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收藏
页码：9511 / 9514
页数：4
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