Novel acceptor-donor-acceptor structured small molecule-based nanoparticles for highly efficient photothermal therapy

被引：47
作者：
Cai, Yu [1 ]
Wei, Zheng [1 ,2 ]
Song, Chuanhui [1 ,3 ]
Tang, Chuanchao [1 ,3 ]
Huang, Xiaoyu [4 ,5 ]
Hu, Qingang [1 ,3 ]
Dong, Xiaochen [4 ,5 ]
Han, Wei [1 ,3 ]
机构：
[1] Nanjing Univ, Sch Med, Nanjing Stomatol Hosp, Cent Lab Stomatol, 30 Zhongyang Rd, Nanjing 210008, Jiangsu, Peoples R China
[2] Nanjing Univ, Sch Med, Nanjing Stomatol Hosp, Pediat Dent, 30 Zhongyang Rd, Nanjing 210008, Jiangsu, Peoples R China
[3] Nanjing Univ, Sch Med, Nanjing Stomatol Hosp, Dept Oral & Maxillofacial Surg, 30 Zhongyang Rd, Nanjing 210008, Jiangsu, Peoples R China
[4] Nanjing Tech Univ NanjingTech, KLOFE, 30 South Puzhu Rd, Nanjing 211800, Jiangsu, Peoples R China
[5] Nanjing Tech Univ NanjingTech, IAM, 30 South Puzhu Rd, Nanjing 211800, Jiangsu, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 61期
关键词：
ORGANIC NANOPARTICLES; CANCER; PHOTOSENSITIZER; NANODRUG; AGENT;
D O I：
10.1039/c9cc04195h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, acceptor-donor-acceptor structured small molecule (ITIC) based nanoparticles (NPs) were explored for photothermal therapy application. ITIC NPs show red-shift absorption in the near-infrared region, high photostability, and high photothermal conversion efficiency under laser irradiation, presenting both excellent cancer cell cytotoxicity in vitro and tumor ablation in vivo.
引用
收藏
页码：8967 / 8970
页数：4
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