Diagnostic immunology in celiac disease

被引：0

作者：

Dickey, William ^{[1
]}

机构：

[1] Altnagelvin Hosp, Dept Gastroenterol, Londonderry BT47 6SB, North Ireland

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2009年 / 5卷 / 04期

关键词：

antiendomysial antibody; autoimmunity; celiac disease; enteropathy; gluten; transglutaminase; ANTITISSUE TRANSGLUTAMINASE ANTIBODIES; ANTI-ENDOMYSIAL ANTIBODIES; GLUTEN-FREE DIET; HUMAN TISSUE-TRANSGLUTAMINASE; SELECTIVE IGA DEFICIENCY; IRRITABLE-BOWEL-SYNDROME; PRIMARY-CARE; CLINICAL CHARACTERISTICS; INTRAEPITHELIAL LYMPHOCYTOSIS; DERMATITIS-HERPETIFORMIS;

D O I：

10.1586/ECI.09.26

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Serum autoantibodies to transglutaminase and endomysium are found in the majority of patients with celiac disease, an autoimmune multisystem disorder affecting approximately 1 % of Western and Middle-Eastern populations. Detection of these antibodies plays a crucial role in the diagnosis of celiac disease. The aim of this review is to summarize recent publications in this field, with particular focus on the applications and limitations of celiac autoantibody testing in routine clinical practice.

引用

页码：471 / 479

页数：9

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