Microanalysis of the human skin structure: preliminary results

被引：16
作者：
Moretto, P
Surleve-Bazeille, JE
Licu, D
Michelet, C
Stoedzel, P
机构：
[1] CEN Bordeaux Gradignan, F-33175 Gradignan, France
[2] Univ Bordeaux 1, Lab Facteurs Def & Regulat Cellulaire, F-33405 Talence, France
[3] Passage Europe, Inst Rech Pierre Fabre, F-31415 Toulouse, France
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 1999年 / 158卷 / 1-4期
关键词：
skin; physiology; minerals; microanalysis; micro-PIXE; scanning proton microprobe;
D O I：
10.1016/S0168-583X(99)00346-8
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
in this paper, we report micro-PIXE analysis of normal human skin sections. The aim of this preliminary study was to investigate the tissue morphology using the distribution pattern of mineral ions. We found that these minerals were compartmentalized enough to constitute useful markers of the tissue ultrastructure. The epidermis and its different skin strata, corneum, granulosum and spinosum, were actually identified on elemental maps. The present work also provided additional useful information about minerals in the intradermal part of hair tracts. Methodological points will be evoked on the basis of this experience, more especially those concerning the sampling procedure. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：386 / 392
页数：7
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