An efficient synthesis of [1,4]pyridazinooxazine[3,4-a]tetrahydro isoquinolines

被引：21

作者：

Cho, SD

Park, YD

Kim, JJ

Joo, WH

Shiro, M

Esser, L

Falck, JR

Ahn, CJ

Shin, DS

Yoon, YJ ^{[1
]}

机构：

[1] Gyeongsang Natl Univ, Dept Chem, Chinju 600701, South Korea

[2] Gyeongsang Natl Univ, Life Sci Res Inst, Chinju 600701, South Korea

[3] Changwon Natl Univ, Res Inst Basic Sci, Chang Won 641773, South Korea

[4] Changwon Natl Univ, Dept Biol & Chem, Chang Won 641773, South Korea

[5] Rigaku Corp, Akishima, Tokyo 1968666, Japan

[6] Univ Texas, SW Med Ctr, Dept Biochem, Dallas, TX 75390 USA

来源：

TETRAHEDRON | 2004年 / 60卷 / 17期

关键词：

pyridazino[4,5-b]1,4]oxazine; tetracyclic isoquinolines;

D O I：

10.1016/j.tet.2004.03.011

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of fused isoquinoline-pyridazinooxazine chimera were prepared in good overall yield from phenethylamide I and 4,5-dichloropyridazin-3-one 2 via Smiles rearrangement and Pictet-Spengler cyclization. (C) 2004 Elsevier Ltd. All rights reserved.

引用

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页码：3763 / 3773

页数：11

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