An efficient synthesis of [1,4]pyridazinooxazine[3,4-a]tetrahydro isoquinolines

被引：21
作者：
Cho, SD
Park, YD
Kim, JJ
Joo, WH
Shiro, M
Esser, L
Falck, JR
Ahn, CJ
Shin, DS
Yoon, YJ [1 ]
机构：
[1] Gyeongsang Natl Univ, Dept Chem, Chinju 600701, South Korea
[2] Gyeongsang Natl Univ, Life Sci Res Inst, Chinju 600701, South Korea
[3] Changwon Natl Univ, Res Inst Basic Sci, Chang Won 641773, South Korea
[4] Changwon Natl Univ, Dept Biol & Chem, Chang Won 641773, South Korea
[5] Rigaku Corp, Akishima, Tokyo 1968666, Japan
[6] Univ Texas, SW Med Ctr, Dept Biochem, Dallas, TX 75390 USA
来源：
TETRAHEDRON | 2004年 / 60卷 / 17期
关键词：
pyridazino[4,5-b]1,4]oxazine; tetracyclic isoquinolines;
D O I：
10.1016/j.tet.2004.03.011
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of fused isoquinoline-pyridazinooxazine chimera were prepared in good overall yield from phenethylamide I and 4,5-dichloropyridazin-3-one 2 via Smiles rearrangement and Pictet-Spengler cyclization. (C) 2004 Elsevier Ltd. All rights reserved.
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收藏
页码：3763 / 3773
页数：11
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