Clinical presentation and differential diagnosis of dementia with Lewy bodies: a review

被引：17
作者：
Morra, L. F. [1 ]
Donovick, P. J. [1 ]
机构：
[1] SUNY Binghamton, Binghamton, NY 13902 USA
来源：
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY | 2014年 / 29卷 / 06期
关键词：
differential diagnosis; dementia; dementia with Lewy bodies; aging; alpha synucleins; SLEEP BEHAVIOR DISORDER; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; DOPAMINERGIC DEGENERATION; COGNITIVE IMPAIRMENT; CEREBRAL ATROPHY; BODY DEMENTIA; DLB; MRI; FEATURES;
D O I：
10.1002/gps.4039
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Background Dementia with Lewy bodies is one of the most prevalent dementia diagnoses. However, differential diagnosis between dementia with Lewy bodies, Alzheimer's disease, and Parkinson's disease with dementia can still be very difficult given the overlap in neuropathology, clinical presentation, cognitive, and neuroanatomical changes. Method A literature review of dementia with Lewy bodies, Alzheimer's disease, and Parkinson's disease with dementia was conducted using PubMed. Results and Implications Accurate diagnosis of dementia with Lewy bodies is crucial in order to more accurately predict the progression of the disease and negative side effects from pharmacological treatment. The differences and similarities between dementia with Lewy bodies, Alzheimer's disease, and Parkinson's disease with dementia are highlighted in order to aid clinicians in differential diagnosis. Copyright (c) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码：569 / 576
页数：8
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