In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline

被引:8
作者
Mendler, Jason H. [1 ]
Maharry, Kati [1 ,2 ]
Becker, Heiko [1 ]
Eisfeld, Ann-Kathrin [1 ]
Senter, Leigha [1 ]
Mrozek, Krzysztof [1 ]
Kohlschmidt, Jessica [1 ,2 ]
Metzeler, Klaus H. [1 ]
Schwind, Sebastian [1 ]
Whitman, Susan P. [1 ]
Khalife, Jihane [1 ]
Caligiuri, Michael A. [1 ]
Klisovic, Rebecca B. [1 ]
Moore, Joseph O. [3 ]
Carter, Thomas H. [4 ]
Marcucci, Guido [1 ]
Bloomfield, Clara D. [1 ]
机构
[1] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA
[2] Mayo Clin, Alliance Clin Trials Oncol Stat & Data Ctr, Rochester, MN USA
[3] Duke Univ, Med Ctr, Durham, NC USA
[4] Univ Iowa, Iowa City, IA USA
关键词
acute myeloid leukemia; RUNX1; NPM1; mutations; mutational interrelationships; GROUP-B; YOUNGER; CANCER; EXPRESSION; PSC-833; ADULTS; GENE;
D O I
10.3324/haematol.2013.089904
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E92 / E94
页数:3
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