共 43 条
- [31] Therapeutic Targeting of Interferon Regulatory Factor 4 with Next Generation Antisense Oligonucleotides Produces Robust In Vivo Antitumor Activity in Preclinical Models of Multiple MyelomaBLOOD, 2017, 130Zhou, TianyuanSchmidt, JoannaKim, YoungsooMacLeod, A. Robert
- [32] AT-101 downregulates BCL2 and MCL1 and potentiates the cytotoxic effects of lenalidomide and dexamethasone in preclinical models of multiple myeloma and Waldenstrom macroglobulinaemiaBRITISH JOURNAL OF HAEMATOLOGY, 2014, 164 (03) : 352 - 365Paulus, AneelChitta, KasyapaAkhtar, SharoonPersonett, DavidMiller, Kena C.Thompson, Kevin J.Carr, JenniferKumar, ShajiRoy, VivekAnsell, Stephen M.Mikhael, Joseph R.Dispenzieri, AngelaReeder, Craig B.Rivera, Candido E.Foran, JamesChanan-Khan, Asher
- [33] A Novel CD138-Targeting Monoclonal Antibody Induces Potent Myeloma Killing and Further Synergizes with IMiDs or Bortezomib in in Vitro and In Vivo Preclinical Models of Human Multiple MyelomaBLOOD, 2020, 136Yu, TengtengChaganty, BharatLin, LiangXing, LijieRamakrishnan, BoopathyWen, KennethHsieh, Phillip A.Wollacott, AndrewViswanathan, KarthikAdari, HedyCho, Shih-FengLi, YuyinYang, WenjuanChen, HailinXu, YanAn, GangQiu, LuguiMunshi, Nikhil C.Babcock, GregoryShriver, ZachMyette, JamesAnderson, KennethTai, Yu-Tzu
- [34] Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma ModelsMOLECULAR CANCER THERAPEUTICS, 2016, 15 (05) : 1132 - 1144Punnoose, Elizabeth A.Leverson, Joel D.Peale, FranklinBoghaert, Erwin R.Belmont, Lisa D.Tan, NguyenYoung, AmyMitten, MichaelIngalla, EllenDarbonne, Walter C.Oleksijew, AnatolTapang, PaulYue, PengOeh, JasonLee, LeslieMaiga, SophieFairbrother, Wayne J.Amiot, MartineSouers, Andrew J.Sampath, Deepak
- [35] Induction of apoptosis and anti-tumor effects of a novel pan inhibitor of Bcl-2 and Mcl-1 apogossypolone (ApoG2) in multiple myeloma cells.BLOOD, 2006, 108 (11) : 735A - 735ALin, JieWu, YongjiWang, ShujieYang, DajunZhao, Yongqiang
- [36] Targeting MCL-1 and BCL-2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non-Hodgkin lymphoma: Results from preclinical models and a Phase Ib studyAMERICAN JOURNAL OF HEMATOLOGY, 2023, 98 (03) : 449 - 463Lasater, Elisabeth A.Amin, Dhara N.Bannerji, RajatMali, Raghuveer SinghBarrett, KathyRys, Ryan N.Oeh, JasonLin, EvaSterne-Weiler, TimIngalla, Ellen ReiGo, MaryAnnYu, Shang-FanKrem, Maxwell M.Arthur, ChrisHahn, UweJohnston, AnnaKarur, VinitKhan, NadiaMarlton, PaulaPhillips, TycelGritti, GiuseppeSeymour, John F.Tani, MonicaYuen, SamMartin, ScottChang, Matthew T.Rose, Christopher M.Pham, Victoria C.Polson, Andrew G.Chang, YiMengWever, ClaudiaJohnson, Nathalie A.Jiang, YanwenHirata, JamieSampath, DeepakMusick, LisaFlowers, Christopher R.Wertz, Ingrid E.
- [37] Dinaciclib synergizes with BH3 mimetics targeting BCL-2 and BCL-XL in multiple myeloma cell lines partially dependent on MCL-1 and in plasma cells from patientsMOLECULAR ONCOLOGY, 2023, 17 (12) : 2507 - 2525Beltran-Visiedo, ManuelJimenez-Alduan, NeliaDiez, RosanaCuenca, MartaBenedi, AndreaSerrano-Del Valle, AlfonsoAzaceta, GemmaPalomera, LuisPeperzak, VictorAnel, AlbertoNaval, JavierMarzo, Isabel
- [38] The Preclinical Activities of PTC596, a Novel Tubulin Binding Agent That Down-Regulates BMI1, Alone and in Combination with Bortezomib in Multiple MyelomaBLOOD, 2019, 134Nagai, YurieMimura, NaoyaRizq, OlaIsshiki, YusukeOshima, MotohikoRizk, MohamedSaraya, AtsunoriKoide, ShuheiNakajima-Takagi, YaekoMiyota, MakikoOshima-Hasegawa, NagisaTsukamoto, ShokichiMitsukawa, ShioTakeda, YusukeOhwada, ChikakoTakeuchi, MasahiroIseki, TohruNakaseko, ChiakiSheedy, JosephineWeetall, MarlaIwama, AtsushiSakaida, Emiko
- [39] Discovery and Preclinical Development of Novel CD74-Targeting Antibody-Drug Conjugates (ADCs) with Significant Activity in Multiple Myeloma (MM) Cell Lines and Xenograft ModelsBLOOD, 2016, 128 (22)Abrahams, CristinaLi, XiaofanYu, AbigailKrimm, StellanieKahana, JasonNarla, Rama KrishnaSchwartz, EricBoylan, JohnHoffmann, HeidiSteiner, AlexanderZawada, JamesStephenson, HeatherBruhns, MaureenDeAlmeida, VenitaMatheny, ShannonBussell, StuartGalan, AdamKline, ToniVasquez, NickiYam, AliceStafford, RyanHeinsohn, HenrySato, AaronMolina, ArturoHallam, TrevorLupher, Mark, Jr.
- [40] Targeting of the E3 ubiquitin-protein ligase HUWE1 impairs DNA repair capacity and tumor growth in preclinical multiple myeloma modelsSCIENTIFIC REPORTS, 2020, 10 (01)Kunz, ViktoriaBommert, Kathryn S.Kruk, JessicaSchwinning, DanielChatterjee, ManikStuehmer, ThorstenBargou, RalfBommert, Kurt