From embryos to embryonic stem cells: biopolitics and therapeutic potential

被引:6
作者
Cedar, S. H. [1 ]
Cooke, J. A.
Luo, Z.
Patel, M. J.
Minger, S. L.
机构
[1] Kings Coll London, Stem Cell Biol Lab, Wolfson Ctr Age Related Dis, London SE1 1UL, England
[2] S Bank Univ, Fac Hlth & Social Care, London SE1 0AA, England
基金
英国医学研究理事会;
关键词
embryonic stem cells; ESC; multipotent; pluripotent; somatic stem cells; transplantation;
D O I
10.1016/S1472-6483(10)60664-5
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The inner cell mass of the preimplantation blastocyst, from which all the cells of the body develop, is a source of embryonic stem cells. These cells can be maintained in their undifferentiated state over long periods in culture and yet retain their pluripotency. The generation of human stem cells capable of differentiating into all the cell types of the human body opens the way for the use of these cells in therapeutic transplantation for a myriad of diseases. However, as discussed here, there are a number of logistical, biological, and clinical hurdles that must be overcome prior to the use of these cells in routine clinical practice.
引用
收藏
页码:725 / 731
页数:7
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