Electrochemical partial fluorination of organic compounds. 74. Efficient anodic synthesis of 2-fluoro- and 2,3-difluoro-2,3-dihydrobenzofuran derivatives

被引：22

作者：

Dawood, KM

Fuchigami, T ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

[2] Tokyo Inst Technol, Dept Elect Chem, Midori Ku, Yokohama, Kanagawa 227, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 16期

关键词：

D O I：

10.1021/jo035871g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Anodic fluorination of 3-substituted benzofuran derivatives in a variety of fluoride salts resulted in the formation of three fluorinated products; two stereoisomers of 2,3-difluoro-2,3-dihydrobenzofuran (cis and trans) and cis-2-fluoro-3-hydroxy-2,3-dihydrobenzofuran derivatives. Dehydrofluorination of the main products, cis-difluoro derivatives, furnished the nonaromatic 2-fluoro-3-benzofuranyledene derivatives instead of the aromatic 2-fluorobenzofuran derivatives.

引用

页码：5302 / 5306

页数：5

共 26 条

[1]

[Anonymous], ADV ELECT TRANSFER C

[2]

[Anonymous], 1991, Fluorine in Bioorganic Chemistry

[3] NATURALLY-OCCURRING DIBENZOFURANS .4. SYNTHESIS OF DIBENZOFURANDIOLS BY ANNELATION OF BENZOFURANS [J].