Prompt Resolution of Hypoglycemia by Hepatic Transarterial Embolization for Malignant Insulinoma with Multiple Liver Metastases

被引：0

作者：

Muro, Shinichiro ^{[1
]}

Nasu, Junichiro ^{[1
]}

Harada, Ryo ^{[1
]}

Matsubara, Minoru ^{[1
]}

Nakarai, Asuka ^{[1
]}

Kanzaki, Hiromitsu ^{[1
]}

Tsutsumi, Kouichiro ^{[1
]}

Kato, Hironari ^{[1
]}

Tanaka, Takehiro ^{[2
]}

Fujiwara, Hiroyasu ^{[3
]}

Uno, Masatoshi ^{[5
]}

Okada, Hiroyuki ^{[4
]}

Yamamoto, Kazuhide ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Gastroenterol & Hepatol, Okayama 7008558, Japan

[2] Okayama Univ Hosp, Dept Pathol, Okayama 7008558, Japan

[3] Okayama Univ Hosp, Dept Radiol, Okayama 7008558, Japan

[4] Okayama Univ Hosp, Dept Endoscopy, Okayama 7008558, Japan

[5] Kaneda Hosp, Maniwa City, Okayama 7193193, Japan

来源：

ACTA MEDICA OKAYAMA | 2014年 / 68卷 / 05期

关键词：

malignant insulinoma; hypoglycemia; liver metastases; transarterial embolization; neuroendocrine tumor; NEUROENDOCRINE TUMORS; CISPLATIN; ETOPOSIDE;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia.

引用

页码：307 / 311

页数：5

共 14 条

[1] Selective therapeutic embolization in malignant insulinoma [J].