Reset osmostat in pregnancy: a case report

被引：7

作者：

Harris, Kemoy ^{[1
]}

Shankar, Ravi ^{[2
]}

Black, Karen ^{[3
]}

Rochelson, Burton ^{[1
]}

机构：

[1] Hofstra North Shore LIJ Sch Med, Div Maternal Fetal Med, Dept Obstet & Gynecol, Hempstead, NY USA

[2] Bon Secours Med Grp, Div Maternal Fetal Med, Dept Obstet & Gynecol, Richmond, VA USA

[3] Hofstra North Shore LIJ Sch Med, Dept Radiol, Hempstead, NY USA

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2014年 / 27卷 / 05期

关键词：

Anti-diuretic hormone; hyponatremia; osmolality; SIADH; sodium; VASOPRESSIN; HYPONATREMIA; SECRETION; VARIANT; WATER;

D O I：

10.3109/14767058.2013.819333

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The reset osmostat syndrome, a form of inappropriate antidiuretic hormone secretion (SIADH), occurs when the threshold for antidiuretic hormone secretion is moved downward. There is evidence to suggest a "reset osmostat phenomenon'' in normal pregnancies, whereby the average plasma-osmolality is decreased by 5-10 mOsm/kg. We present a case of a non-physiologic reset osmostat in a pregnant patient, thought to be caused by large intracranial arteriovenous malformations and intraventricular hemorrhage. The presence of a reset osmostat should be suspected in any patient with apparent SIADH who has mild hyponatremia that is stable over many days despite variations in sodium and water intake. Therapeutic efforts to raise the serum sodium concentration appear to be unnecessary.

引用

页码：530 / 533

页数：4

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